Research ArticleMitosis
Global assessment of its network dynamics reveals that the kinase Plk1 inhibits the phosphatase PP6 to promote Aurora A activity
- Arminja N. Kettenbach1,2,*,
- Kate A. Schlosser2,
- Scott P. Lyons1,
- Isha Nasa1,
- Jiang Gui3,
- Mark E. Adamo2, and
- Scott A. Gerber1,2,4,*
- 1Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
- 2Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.
- 3Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.
- 4Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
- ↵*Corresponding author. Email: arminja.n.kettenbach{at}dartmouth.edu (A.N.K.); scott.a.gerber{at}dartmouth.edu (S.A.G.)
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Science Signaling 15 May 2018:
Vol. 11, Issue 530, eaaq1441
DOI: 10.1126/scisignal.aaq1441
Vol. 11, Issue 530, eaaq1441
DOI: 10.1126/scisignal.aaq1441
Arminja N. Kettenbach
Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.
Kate A. Schlosser
Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.
Scott P. Lyons
Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
Isha Nasa
Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
Jiang Gui
Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.
Mark E. Adamo
Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.
Scott A. Gerber
Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
