Integration of protein phosphorylation, acetylation, and methylation data sets to outline lung cancer signaling networks

Mark Grimes; Benjamin Hall; Lauren Foltz; Tyler Levy; Klarisa Rikova; Jeremiah Gaiser; William Cook; Ekaterina Smirnova; Travis Wheeler; Neil R. Clark; Alexander Lachmann; Bin Zhang; Peter Hornbeck; Avi Ma’ayan; Michael Comb

doi:10.1126/scisignal.aaq1087

Research ResourceCancer

Integration of protein phosphorylation, acetylation, and methylation data sets to outline lung cancer signaling networks

Mark Grimes¹,*,
View ORCID ProfileBenjamin Hall²,
Lauren Foltz¹,
Tyler Levy²,
Klarisa Rikova²,
Jeremiah Gaiser¹,
William Cook¹,
View ORCID ProfileEkaterina Smirnova¹,
View ORCID ProfileTravis Wheeler¹,
Neil R. Clark³,
View ORCID ProfileAlexander Lachmann³,
Bin Zhang²,
View ORCID ProfilePeter Hornbeck²,
View ORCID ProfileAvi Ma’ayan ³, and
Michael Comb²

¹Division of Biological Sciences, and Department of Computer Science, Department of Mathematical Sciences, University of Montana, Missoula, MT 59812, USA.
²Cell Signaling Technology, Danvers, MA 01923, USA.
³Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, BD2K-LINCS (Big Data to Knowledge Library of Integrated Network-based Cellular Signatures) Data Coordination and Integration Center, Icahn School of Medicine, Mount Sinai, New York, NY 10029, USA.

↵*Corresponding author. Email: mark.grimes{at}mso.umt.edu

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Science Signaling 22 May 2018:
Vol. 11, Issue 531, eaaq1087
DOI: 10.1126/scisignal.aaq1087

Mark Grimes

1Division of Biological Sciences, and Department of Computer Science, Department of Mathematical Sciences, University of Montana, Missoula, MT 59812, USA.

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For correspondence: mark.grimes@mso.umt.edu

Benjamin Hall

2Cell Signaling Technology, Danvers, MA 01923, USA.

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ORCID record for Benjamin Hall

Lauren Foltz

1Division of Biological Sciences, and Department of Computer Science, Department of Mathematical Sciences, University of Montana, Missoula, MT 59812, USA.

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Tyler Levy

2Cell Signaling Technology, Danvers, MA 01923, USA.

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Klarisa Rikova

2Cell Signaling Technology, Danvers, MA 01923, USA.

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Jeremiah Gaiser

1Division of Biological Sciences, and Department of Computer Science, Department of Mathematical Sciences, University of Montana, Missoula, MT 59812, USA.

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William Cook

1Division of Biological Sciences, and Department of Computer Science, Department of Mathematical Sciences, University of Montana, Missoula, MT 59812, USA.

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Ekaterina Smirnova

1Division of Biological Sciences, and Department of Computer Science, Department of Mathematical Sciences, University of Montana, Missoula, MT 59812, USA.

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ORCID record for Ekaterina Smirnova

Travis Wheeler

1Division of Biological Sciences, and Department of Computer Science, Department of Mathematical Sciences, University of Montana, Missoula, MT 59812, USA.

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Neil R. Clark

3Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, BD2K-LINCS (Big Data to Knowledge Library of Integrated Network-based Cellular Signatures) Data Coordination and Integration Center, Icahn School of Medicine, Mount Sinai, New York, NY 10029, USA.

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Alexander Lachmann

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Bin Zhang

2Cell Signaling Technology, Danvers, MA 01923, USA.

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Peter Hornbeck

2Cell Signaling Technology, Danvers, MA 01923, USA.

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Avi Ma’ayan

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ORCID record for Avi Ma’ayan

Michael Comb

2Cell Signaling Technology, Danvers, MA 01923, USA.

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