Research ArticleCell Biology
Phagocytosed photoreceptor outer segments activate mTORC1 in the retinal pigment epithelium
- View ORCID ProfileBo Yu1,
- View ORCID ProfileAnuoluwapo Egbejimi1,
- View ORCID ProfileRachayata Dharmat2,
- Pei Xu1,
- Zhenyang Zhao1,
- Bo Long1,*,
- View ORCID ProfileHongyu Miao3,
- Rui Chen2,4,
- View ORCID ProfileTheodore G. Wensel4,
- Jiyang Cai1,5, and
- View ORCID ProfileYan Chen1,5,†
- 1Department of Ophthalmology and Visual Science, University of Texas Medical Branch, Galveston, TX 77555, USA.
- 2Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
- 3Department of Biostatistics and Data Science, School of Public Health, University of Texas Health Science Center, Houston, TX 77030, USA.
- 4Department of Biochemistry, Baylor College of Medicine, Houston, TX 77030, USA.
- 5Department of Neuroscience, Cell Biology and Anatomy, University of Texas Medical Branch, Galveston, TX 77555, USA.
- ↵†Corresponding author. Email: yachen1{at}utmb.edu
↵* Deceased.
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Science Signaling 29 May 2018:
Vol. 11, Issue 532, eaag3315
DOI: 10.1126/scisignal.aag3315
Vol. 11, Issue 532, eaag3315
DOI: 10.1126/scisignal.aag3315
Bo Yu
1Department of Ophthalmology and Visual Science, University of Texas Medical Branch, Galveston, TX 77555, USA.
Anuoluwapo Egbejimi
1Department of Ophthalmology and Visual Science, University of Texas Medical Branch, Galveston, TX 77555, USA.
Rachayata Dharmat
2Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Pei Xu
1Department of Ophthalmology and Visual Science, University of Texas Medical Branch, Galveston, TX 77555, USA.
Zhenyang Zhao
1Department of Ophthalmology and Visual Science, University of Texas Medical Branch, Galveston, TX 77555, USA.
Bo Long
1Department of Ophthalmology and Visual Science, University of Texas Medical Branch, Galveston, TX 77555, USA.
Hongyu Miao
3Department of Biostatistics and Data Science, School of Public Health, University of Texas Health Science Center, Houston, TX 77030, USA.
Rui Chen
2Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
4Department of Biochemistry, Baylor College of Medicine, Houston, TX 77030, USA.
Theodore G. Wensel
4Department of Biochemistry, Baylor College of Medicine, Houston, TX 77030, USA.
Jiyang Cai
1Department of Ophthalmology and Visual Science, University of Texas Medical Branch, Galveston, TX 77555, USA.
5Department of Neuroscience, Cell Biology and Anatomy, University of Texas Medical Branch, Galveston, TX 77555, USA.
Yan Chen
1Department of Ophthalmology and Visual Science, University of Texas Medical Branch, Galveston, TX 77555, USA.
5Department of Neuroscience, Cell Biology and Anatomy, University of Texas Medical Branch, Galveston, TX 77555, USA.
