Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization

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  Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization

  By Elke Miess, Arisbel B. Gondin, Arsalan Yousuf, Ralph Steinborn, Nadja Mösslein, Yunshi Yang, Martin Göldner, Julia G. Ruland, Moritz Bünemann, Cornelius Krasel, MacDonald J. Christie, Michelle L. Halls, Stefan Schulz, Meritxell Canals

  Science Signaling17 Jul 2018

  High-efficacy opioids enhance receptor desensitization due to rapid and sustained GRK2/β-arrestin interactions.

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  Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization

  By Elke Miess, Arisbel B. Gondin, Arsalan Yousuf, Ralph Steinborn, Nadja Mösslein, Yunshi Yang, Martin Göldner, Julia G. Ruland, Moritz Bünemann, Cornelius Krasel, MacDonald J. Christie, Michelle L. Halls, Stefan Schulz, Meritxell Canals

  Science Signaling17 Jul 2018

  High-efficacy opioids enhance receptor desensitization due to rapid and sustained GRK2/β-arrestin interactions.

  • Supplementary Materials

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