Editors' ChoiceGENE THERAPY

CRISPR, cancer, and p53

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Science Signaling  17 Jul 2018:
Vol. 11, Issue 539, eaau7344
DOI: 10.1126/scisignal.aau7344

CRISPR-Cas9 genome editing is most efficient in cells lacking functional p53 protein, a phenotype common to cancer cells.

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