24 July 2018
Vol 11, Issue 540

About The Cover

Cover image expansion

Online Cover This week features a Research Article that shows how integrated modeling of gene expression, cell cycling, and DNA damage response and cell survival dynamics can predict the efficacy of drug-chemotherapy combinations. The model correctly predicted the synergy of sequential liposomal delivery of irinotecan and the ATR inhibitor VE-822 in a subcutaneous xenograft model of cervical cancer. [Image: CactusStudio/Shutterstock]