Research ArticleStress responses
Cells alter their tRNA abundance to selectively regulate protein synthesis during stress conditions
- View ORCID ProfileMarc Torrent1,2,*,†,
- Guilhem Chalancon1,*,
- View ORCID ProfileNatalia S. de Groot1,‡,
- View ORCID ProfileArthur Wuster1,§, and
- View ORCID ProfileM. Madan Babu1,†
- 1Laboratory of Molecular Biology, Medical Research Council, Francis Crick Avenue, CB2 0QH Cambridge, UK.
- 2Systems Biology of Infection Lab, Department of Biochemistry and Molecular Biology, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.
- ↵†Corresponding author. Email: marc.torrent{at}uab.cat (M.T.); madanm{at}mrc-lmb.cam.ac.uk (M.M.B.)
↵* Joint first authors.
↵‡ Present address: Center for Genomic Regulation, Parc de Recerca Biomèdica de Barcelona, Aiguader 88, 08003 Barcelona, Spain.
↵§ Present address: Department of Human Genetics and Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, CA 94080, USA.
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Science Signaling 04 Sep 2018:
Vol. 11, Issue 546, eaat6409
DOI: 10.1126/scisignal.aat6409
Vol. 11, Issue 546, eaat6409
DOI: 10.1126/scisignal.aat6409
Marc Torrent
1Laboratory of Molecular Biology, Medical Research Council, Francis Crick Avenue, CB2 0QH Cambridge, UK.
2Systems Biology of Infection Lab, Department of Biochemistry and Molecular Biology, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.
Guilhem Chalancon
1Laboratory of Molecular Biology, Medical Research Council, Francis Crick Avenue, CB2 0QH Cambridge, UK.
Natalia S. de Groot
1Laboratory of Molecular Biology, Medical Research Council, Francis Crick Avenue, CB2 0QH Cambridge, UK.
Arthur Wuster
1Laboratory of Molecular Biology, Medical Research Council, Francis Crick Avenue, CB2 0QH Cambridge, UK.
M. Madan Babu
1Laboratory of Molecular Biology, Medical Research Council, Francis Crick Avenue, CB2 0QH Cambridge, UK.