Research ArticleInflammation MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity Bishuang Cai1,*, Canan Kasikara1, View ORCID ProfileAmanda C. Doran1, Rajasekhar Ramakrishnan2, Raymond B. Birge3, and View ORCID ProfileIra Tabas1,*1Departments of Medicine, Pathology and Cell Biology, and Physiology, Columbia University, New York, NY 10032, USA.2Department of Pediatrics, Columbia University, New York, NY 10032, USA.3Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers University, New Jersey Medical School Cancer Center, Newark, NJ 07103, USA.↵*Corresponding author. Email: bc2586{at}columbia.edu (B.C.); iat1{at}columbia.edu (I.T.) See allHide authors and affiliations Science Signaling 25 Sep 2018:Vol. 11, Issue 549, eaar3721DOI: 10.1126/scisignal.aar3721 Bishuang Cai 1Departments of Medicine, Pathology and Cell Biology, and Physiology, Columbia University, New York, NY 10032, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site For correspondence: bc2586@columbia.edu iat1@columbia.edu Canan Kasikara 1Departments of Medicine, Pathology and Cell Biology, and Physiology, Columbia University, New York, NY 10032, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Amanda C. Doran 1Departments of Medicine, Pathology and Cell Biology, and Physiology, Columbia University, New York, NY 10032, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Amanda C. Doran Rajasekhar Ramakrishnan 2Department of Pediatrics, Columbia University, New York, NY 10032, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Raymond B. Birge 3Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers University, New Jersey Medical School Cancer Center, Newark, NJ 07103, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Ira Tabas 1Departments of Medicine, Pathology and Cell Biology, and Physiology, Columbia University, New York, NY 10032, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Ira Tabas For correspondence: bc2586@columbia.edu iat1@columbia.edu Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 11 no. 549 DOI: https://doi.org/10.1126/scisignal.aar3721 PubMed: 30254055 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: Received October 31, 2017Accepted September 8, 2018 . Copyright & Usage: Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works http://www.sciencemag.org/about/science-licenses-journal-article-reuseThis is an article distributed under the terms of the Science Journals Default License. Author Information Altmetric Article usage Article lifetimeLast 6 monthsThis monthArticle usage: September 2018 to March 2021 AbstractFullPdf Sep 20182259272186 Oct 2018920220175 Nov 20182009945 Dec 20181499131 Jan 201914510352 Feb 201916010635 Mar 20191358435 Apr 20191216230 May 20191126520 Jun 20191097116 Jul 20191249923 Aug 20191148816 Sep 201911210026 Oct 2019122367 Nov 2019221052 Dec 2019024263 Jan 2020122060 Feb 2020033371 Mar 2020024456 Apr 20200280103 May 2020032579 Jun 2020229173 Jul 2020029582 Aug 2020025089 Sep 2020325893 Oct 20201263105 Nov 2020225993 Dec 20201274118 Jan 2021729484 Feb 2021031297 Mar 202101317 View Full Text
MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity By Bishuang Cai, Canan Kasikara, Amanda C. Doran, Rajasekhar Ramakrishnan, Raymond B. Birge, Ira Tabas Science Signaling25 Sep 2018 Signaling by the receptor MerTK in macrophages promotes ERK activation and the resolution of inflammation. Supplementary Materials
MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity By Bishuang Cai, Canan Kasikara, Amanda C. Doran, Rajasekhar Ramakrishnan, Raymond B. Birge, Ira Tabas Science Signaling25 Sep 2018 Signaling by the receptor MerTK in macrophages promotes ERK activation and the resolution of inflammation. Supplementary Materials