16 October 2018
Vol 11, Issue 552

About The Cover

Cover image expansion

Online Cover This week features a Research Article that shows how signaling by the growth factor VEGF, secreted from breast cancer cells growing in the bone, causes pain by suppressing potassium ion flux in sensory neurons. The image shows fluorescent staining for a neurofilament protein (green) and the potassium channel TRESK (red) in the dorsal root ganglion from a rat model of bone-metastatic breast cancer. [Image: Yang et al., Science Signaling]