Research ArticleImmunology Crk adaptor proteins mediate actin-dependent T cell migration and mechanosensing induced by the integrin LFA-1 View ORCID ProfileNathan H. Roy1,2, Joanna L. MacKay3, View ORCID ProfileTanner F. Robertson1,2, Daniel A. Hammer3,4, and View ORCID ProfileJanis K. Burkhardt1,2,*1Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA, USA.2Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.3Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.4Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA, USA.↵*Corresponding author. Email: jburkhar{at}pennmedicine.upenn.edu See allHide authors and affiliations Science Signaling 11 Dec 2018:Vol. 11, Issue 560, eaat3178DOI: 10.1126/scisignal.aat3178 Nathan H. Roy 1Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA, USA.2Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Nathan H. Roy Joanna L. MacKay 3Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Tanner F. Robertson 1Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA, USA.2Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Tanner F. Robertson Daniel A. Hammer 3Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.4Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Janis K. Burkhardt 1Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA, USA.2Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Janis K. Burkhardt For correspondence: jburkhar@pennmedicine.upenn.edu Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 11 no. 560 DOI: https://doi.org/10.1126/scisignal.aat3178 PubMed: 30538176 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: Received February 13, 2018Accepted November 20, 2018 . Copyright & Usage: Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works http://www.sciencemag.org/about/science-licenses-journal-article-reuseThis is an article distributed under the terms of the Science Journals Default License. Author Information Altmetric Article usage Article lifetimeLast 6 monthsThis monthArticle usage: December 2018 to April 2021 AbstractFullPdf Dec 20183378321156 Jan 20191727849 Feb 2019855134 Mar 2019632316 Apr 2019342412 May 2019663122 Jun 2019693715 Jul 2019413721 Aug 2019551923 Sep 2019502215 Oct 201947227 Nov 201955137 Dec 2019204416 Jan 202016617 Feb 202047126 Mar 202006126 Apr 202017625 May 202029162 Jun 202005431 Jul 202034620 Aug 202003326 Sep 202004134 Oct 202004625 Nov 202014139 Dec 202015033 Jan 202105234 Feb 202145240 Mar 202145544 Apr 202112521 View Full Text
Crk adaptor proteins mediate actin-dependent T cell migration and mechanosensing induced by the integrin LFA-1 By Nathan H. Roy, Joanna L. MacKay, Tanner F. Robertson, Daniel A. Hammer, Janis K. Burkhardt Science Signaling11 Dec 2018 Crk adaptor proteins mediate integrin signaling–induced T cell migration. Supplementary Materials
Crk adaptor proteins mediate actin-dependent T cell migration and mechanosensing induced by the integrin LFA-1 By Nathan H. Roy, Joanna L. MacKay, Tanner F. Robertson, Daniel A. Hammer, Janis K. Burkhardt Science Signaling11 Dec 2018 Crk adaptor proteins mediate integrin signaling–induced T cell migration. Supplementary Materials