Research ArticleImmunology
CD45 exclusion– and cross-linking–based receptor signaling together broaden FcεRI reactivity
- James H. Felce1,2,3,*,
- Erdinc Sezgin1,*,
- Madina Wane1,2,
- Heather Brouwer1,2,
- Michael L. Dustin3,†,
- Christian Eggeling1,†,‡, and
- Simon J. Davis1,2,†
- 1MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
- 2Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.
- 3Kennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, UK.
- ↵†Corresponding author. Email: simon.davis{at}imm.ox.ac.uk (S.J.D.); christian.eggeling{at}rdm.ox.ac.uk (C.E.); michael.dustin{at}kennedy.ox.ac.uk (M.L.D.)
↵* These authors contributed equally to this work.
↵‡ Present address: Institute of Applied Optics Friedrich-Schiller-University Jena and Leibniz Institute of Photonic Technology e.V., Jena, Germany.
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Science Signaling 18 Dec 2018:
Vol. 11, Issue 561, eaat0756
DOI: 10.1126/scisignal.aat0756
