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Research ArticleImmunology
CD45 exclusion– and cross-linking–based receptor signaling together broaden FcεRI reactivity
- View ORCID ProfileJames H. Felce1,2,3,*,
- View ORCID ProfileErdinc Sezgin1,*,
- View ORCID ProfileMadina Wane1,2,
- View ORCID ProfileHeather Brouwer1,2,
- View ORCID ProfileMichael L. Dustin3,†,
- View ORCID ProfileChristian Eggeling1,†,‡, and
- View ORCID ProfileSimon J. Davis1,2,†
- 1MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
- 2Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.
- 3Kennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, UK.
- ↵†Corresponding author. Email: simon.davis{at}imm.ox.ac.uk (S.J.D.); christian.eggeling{at}rdm.ox.ac.uk (C.E.); michael.dustin{at}kennedy.ox.ac.uk (M.L.D.)
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Science Signaling 18 Dec 2018:
Vol. 11, Issue 561, eaat0756
DOI: 10.1126/scisignal.aat0756
Vol. 11, Issue 561, eaat0756
DOI: 10.1126/scisignal.aat0756
James H. Felce
1MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
2Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.
3Kennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, UK.
Erdinc Sezgin
1MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
Madina Wane
1MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
2Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.
Heather Brouwer
1MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
2Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.
Michael L. Dustin
3Kennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, UK.
Christian Eggeling
1MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
Simon J. Davis
1MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
2Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.
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