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Research ArticleBiochemistry
Activation of atypical protein kinase C by sphingosine 1-phosphate revealed by an aPKC-specific activity reporter
- View ORCID ProfileTaketoshi Kajimoto1,2,*,
- View ORCID ProfileAlisha D. Caliman1,
- Irene S. Tobias1,
- View ORCID ProfileTaro Okada2,
- Caila A. Pilo1,
- An-Angela N. Van1,
- View ORCID ProfileJ. Andrew McCammon1,
- Shun-ichi Nakamura2, and
- View ORCID ProfileAlexandra C. Newton1,*
- 1Department of Pharmacology, University of California at San Diego, La Jolla, CA 92037, USA.
- 2Division of Biochemistry, Department of Biochemistry and Molecular Biology, Graduate School of Medicine, Kobe University, Kobe 650-0017, Japan.
- ↵*Corresponding author. Email: anewton{at}ucsd.edu (A.C.N.); tkajimot{at}med.kobe-u.ac.jp (T.K.)
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Science Signaling 01 Jan 2019:
Vol. 12, Issue 562, eaat6662
DOI: 10.1126/scisignal.aat6662
Vol. 12, Issue 562, eaat6662
DOI: 10.1126/scisignal.aat6662
Taketoshi Kajimoto
1Department of Pharmacology, University of California at San Diego, La Jolla, CA 92037, USA.
2Division of Biochemistry, Department of Biochemistry and Molecular Biology, Graduate School of Medicine, Kobe University, Kobe 650-0017, Japan.
Alisha D. Caliman
1Department of Pharmacology, University of California at San Diego, La Jolla, CA 92037, USA.
Irene S. Tobias
1Department of Pharmacology, University of California at San Diego, La Jolla, CA 92037, USA.
Taro Okada
2Division of Biochemistry, Department of Biochemistry and Molecular Biology, Graduate School of Medicine, Kobe University, Kobe 650-0017, Japan.
Caila A. Pilo
1Department of Pharmacology, University of California at San Diego, La Jolla, CA 92037, USA.
An-Angela N. Van
1Department of Pharmacology, University of California at San Diego, La Jolla, CA 92037, USA.
J. Andrew McCammon
1Department of Pharmacology, University of California at San Diego, La Jolla, CA 92037, USA.
Shun-ichi Nakamura
2Division of Biochemistry, Department of Biochemistry and Molecular Biology, Graduate School of Medicine, Kobe University, Kobe 650-0017, Japan.
Alexandra C. Newton
1Department of Pharmacology, University of California at San Diego, La Jolla, CA 92037, USA.
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