29 January 2019
Vol 12, Issue 566

About The Cover

Cover image expansion

Online Cover This week features a Research Article that demonstrates that the pseudokinase domains of the natriuretic peptide receptors GC-A and GC-B promote receptor activation through an allosteric mechanism that is conserved with catalytically active kinases. The image shows a homology model of the pseudokinase domain of GC-A with the R-spine (red), C-spine (green), and F helix (yellow) highlighted. [Image: Edmund et al./Science Signaling]