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Research ArticleImmunology
Desynchronization of the molecular clock contributes to the heterogeneity of the inflammatory response
- View ORCID ProfileNancy C. Allen1,*,
- View ORCID ProfileNaomi H. Philip1,
- Lucy Hui1,
- View ORCID ProfileXu Zhou1,
- Ruth A. Franklin1,
- View ORCID ProfileYong Kong1,2, and
- View ORCID ProfileRuslan Medzhitov3,†
- 1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
- 2Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06510, USA.
- 3Howard Hughes Medical Institute, Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
- ↵†Corresponding author. Email: ruslan.medzhitov{at}yale.edu
↵* Present address: Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
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Science Signaling 05 Mar 2019:
Vol. 12, Issue 571, eaau1851
DOI: 10.1126/scisignal.aau1851
Vol. 12, Issue 571, eaau1851
DOI: 10.1126/scisignal.aau1851
Nancy C. Allen
1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Naomi H. Philip
1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Lucy Hui
1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Xu Zhou
1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Ruth A. Franklin
1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Yong Kong
1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
2Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06510, USA.
Ruslan Medzhitov
3Howard Hughes Medical Institute, Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
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