12 March 2019
Vol 12, Issue 572

About The Cover

Cover image expansion

Online Cover This week features a Research Article that shows how manganese exposure, associated with Parkinson's disease, promotes the transfer of α-synuclein between neurons and microglia, which induce inflammation and neuronal cell death. The image shows immunofluorescent staining for exosomes (green) and a marker of caveolae-mediated endocytosis (red) in primary murine microglial cells. [Image: Harischandra et al./Science Signaling]