Research ArticleNeuroscience
BDNF increases synaptic NMDA receptor abundance by enhancing the local translation of Pyk2 in cultured hippocampal neurons
- Pedro Afonso1,2,
- Pasqualino De Luca1,3,
- Rafael S. Carvalho1,
- Luísa Cortes1,3,
- Paulo Pinheiro1,3,
- Barbara Oliveiros4,5,
- Ramiro D. Almeida1,6,
- Miranda Mele1,3, and
- Carlos B. Duarte1,7,*
- 1CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
- 2Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.
- 3Institute for Interdisciplinary Research, University of Coimbra (IIIUC), 3030-790 Coimbra, Portugal.
- 4Laboratory of Biostatistics and Medical Informatics, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.
- 5Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.
- 6Health Sciences Program, Department of Medical Sciences, Institute of Biomedicine - iBiMED, University of Aveiro, 3810-193 Aveiro, Portugal.
- 7Department of Life Sciences, University of Coimbra, 3000-456 Coimbra, Portugal.
- ↵*Corresponding author. Email: cbduarte{at}ci.uc.pt
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Science Signaling 18 Jun 2019:
Vol. 12, Issue 586, eaav3577
DOI: 10.1126/scisignal.aav3577
