Contents

Research Articles

• Slow growth determines nonheritable antibiotic resistance in Salmonella enterica

  By Mauricio H. Pontes, Eduardo A. Groisman

  Science Signaling30 Jul 2019 Full AccessRestricted Access

  Slow growth alone determines the persistence of Salmonella after antibiotic treatment.

  • Editor's Summary
  • Abstract
  • Full Text
  • PDF
  • Supplementary Materials

• TNFR1 membrane reorganization promotes distinct modes of TNFα signaling

  By Penny E. Morton, Camille Perrin, James Levitt, Daniel R. Matthews, Richard J. Marsh, Rosemary Pike, David McMillan, Alison Maloney, Simon Poland, Simon Ameer-Beg, Maddy Parsons

  Science Signaling30 Jul 2019 Full AccessRestricted Access

  Nanoscale reorganization of TNFR1 within the plasma membrane promotes the activation of distinct signaling pathways.

  • Editor's Summary
  • Abstract
  • Full Text
  • PDF
  • Supplementary Materials

• Noncompetitive inhibitors of TNFR1 probe conformational activation states

  By Chih Hung Lo, Tory M. Schaaf, Benjamin D. Grant, Colin Kin-Wye Lim, Prachi Bawaskar, Courtney C. Aldrich, David D. Thomas, Jonathan N. Sachs

  Science Signaling30 Jul 2019 Full AccessRestricted Access

  A small molecule that noncompetitively inhibits TNFR1 could be optimized to treat inflammatory diseases.

  • Editor's Summary
  • Abstract
  • Full Text
  • PDF
  • Supplementary Materials