Contents
30 July 2019
Vol 12, Issue 592
Vol 12, Issue 592
Focus
- Slow growth causes bacterial persistence
Formation of Salmonella persister cells depends on slow growth (Pontes and Groisman in 30 July 2019 issue).
Research Articles
- Slow growth determines nonheritable antibiotic resistance in Salmonella enterica
Slow growth alone determines the persistence of Salmonella after antibiotic treatment.
- TNFR1 membrane reorganization promotes distinct modes of TNFα signaling
Nanoscale reorganization of TNFR1 within the plasma membrane promotes the activation of distinct signaling pathways.
- Noncompetitive inhibitors of TNFR1 probe conformational activation states
A small molecule that noncompetitively inhibits TNFR1 could be optimized to treat inflammatory diseases.
Editors' Choice
- New connections: HIPK2 becomes crystal clear
Solving the crystal structure of HIPK2 may lead to therapeutic targeting of this versatile kinase.
About The Cover
Online Cover This week features a Research Article that shows that the persistence of Salmonella enterica serovar Typhimurium after antibiotic treatment depends solely on slow growth. The image shows a scanning electron micrograph of Salmonella Typhimurium. [Image: Nano Creative/Science Source]
