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Research ArticleMitosis
Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression
- Rozita Adib1,
- Jessica M. Montgomery1,
- Joseph Atherton2,
- Laura O’Regan1,
- Mark W. Richards3,
- Kees R. Straatman4,
- Daniel Roth5,
- Anne Straube5,
- Richard Bayliss3,
- Carolyn A. Moores2, and
- Andrew M. Fry1,*
- 1Department of Molecular and Cell Biology, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.
- 2Institute of Structural and Molecular Biology, Birkbeck College, Malet Street, London WC1E 7HX, UK.
- 3Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
- 4Centre for Core Biotechnology Services, University of Leicester, University Road, Leicester LE1 7RH, UK.
- 5Centre for Mechanochemical Cell Biology and Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK.
- ↵*Corresponding author. Email: amf5{at}le.ac.uk
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Science Signaling 13 Aug 2019:
Vol. 12, Issue 594, eaaw2939
DOI: 10.1126/scisignal.aaw2939
Vol. 12, Issue 594, eaaw2939
DOI: 10.1126/scisignal.aaw2939
Rozita Adib
Department of Molecular and Cell Biology, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.
Jessica M. Montgomery
Department of Molecular and Cell Biology, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.
Joseph Atherton
Institute of Structural and Molecular Biology, Birkbeck College, Malet Street, London WC1E 7HX, UK.
Laura O’Regan
Department of Molecular and Cell Biology, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.
Mark W. Richards
Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
Kees R. Straatman
Centre for Core Biotechnology Services, University of Leicester, University Road, Leicester LE1 7RH, UK.
Daniel Roth
Centre for Mechanochemical Cell Biology and Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK.
Anne Straube
Centre for Mechanochemical Cell Biology and Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK.
Richard Bayliss
Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
Carolyn A. Moores
Institute of Structural and Molecular Biology, Birkbeck College, Malet Street, London WC1E 7HX, UK.
Andrew M. Fry
Department of Molecular and Cell Biology, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.
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