20 August 2019
Vol 12, Issue 595

About The Cover

Cover image expansion

Online Cover This week features a Research Article that describes how a metabolic switch in taxane-treated breast cancer cells results in increased reliance on oxidative and non-oxidative glucose metabolism and in resistance to unrelated chemotherapeutics (also see the associated Focus). The image shows immunohistochemistry of breast tumors from taxane-treated mice for the glucose transporter Glut1 (red) and CD44 (green), a marker for the metabolic switch. [Image: Goldman et al./Science Signaling]