Dynamics of drug response informs rational combination regimens

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Science Signaling  20 Aug 2019:
Vol. 12, Issue 595, eaax9742
DOI: 10.1126/scisignal.aax9742

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Metabolic plasticity in cancer has been linked to the development of drug-tolerant populations. In this issue of Science Signaling, Goldman et al. integrate metabolic plasticity with phenotypic state transitions to examine how this reprogramming can be therapeutically exploited.

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