Research ArticleImmunology
SMAC mimetics promote NIK-dependent inhibition of CD4+ TH17 cell differentiation
- View ORCID ProfileJohn Rizk1,
- View ORCID ProfileJoseph Kaplinsky1,
- Rasmus Agerholm1,
- Darshana Kadekar1,
- Fredrik Ivars2,
- William W. Agace1,2,
- View ORCID ProfileW. Wei-Lynn Wong3,
- Matthew J. Szucs4,
- Samuel A. Myers4,
- View ORCID ProfileSteven A. Carr4,
- View ORCID ProfileAri Waisman5, and
- View ORCID ProfileVasileios Bekiaris1,*
- 1Department of Health Technology, Technical University of Denmark, Kemitorvet, Building 202, 2800 Kgs Lyngby, Denmark.
- 2Department of Experimental Medical Science, Lund University, 22184 Lund, Sweden.
- 3Institute of Experimental Immunology, University of Zurich, Winterthurerstrasse 190, Zurich, Switzerland.
- 4Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
- 5Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg University of Mainz, Obere Zahlbacher Str. 67, Mainz 55131, Germany.
- ↵*Corresponding author. Email: vasbek{at}dtu.dk
See allHide authors and affiliations
Science Signaling 27 Aug 2019:
Vol. 12, Issue 596, eaaw3469
DOI: 10.1126/scisignal.aaw3469
Vol. 12, Issue 596, eaaw3469
DOI: 10.1126/scisignal.aaw3469
John Rizk
1Department of Health Technology, Technical University of Denmark, Kemitorvet, Building 202, 2800 Kgs Lyngby, Denmark.
Joseph Kaplinsky
1Department of Health Technology, Technical University of Denmark, Kemitorvet, Building 202, 2800 Kgs Lyngby, Denmark.
Rasmus Agerholm
1Department of Health Technology, Technical University of Denmark, Kemitorvet, Building 202, 2800 Kgs Lyngby, Denmark.
Darshana Kadekar
1Department of Health Technology, Technical University of Denmark, Kemitorvet, Building 202, 2800 Kgs Lyngby, Denmark.
Fredrik Ivars
2Department of Experimental Medical Science, Lund University, 22184 Lund, Sweden.
William W. Agace
1Department of Health Technology, Technical University of Denmark, Kemitorvet, Building 202, 2800 Kgs Lyngby, Denmark.
2Department of Experimental Medical Science, Lund University, 22184 Lund, Sweden.
W. Wei-Lynn Wong
3Institute of Experimental Immunology, University of Zurich, Winterthurerstrasse 190, Zurich, Switzerland.
Matthew J. Szucs
4Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Samuel A. Myers
4Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Steven A. Carr
4Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Ari Waisman
5Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg University of Mainz, Obere Zahlbacher Str. 67, Mainz 55131, Germany.
Vasileios Bekiaris
1Department of Health Technology, Technical University of Denmark, Kemitorvet, Building 202, 2800 Kgs Lyngby, Denmark.
