03 September 2019
Vol 12, Issue 597

About The Cover

Cover image expansion

Online Cover This week features a Research Article that shows that an evolutionarily conserved family of phosphatases enables cells to resist the toxic metabolic effects of 2-deoxyglucose (2-DG). The image shows the footprint left after washing by a colony of yeast with a mutation in cyc8, a transcriptional co-repressor that suppresses the expression of genes encoding 2-DG–detoxifying phosphatases. [Image: Sébastien Léon/Institute Jacques Monod, CNRS, France]