17 September 2019
Vol 12, Issue 599

About The Cover

Cover image expansion

Online Cover This week features a Research Article that shows that the tumor-derived cytokine TGF-β inhibits mitochondrial respiration in CD4+ T lymphocytes, leading to reduced IFN-γ production and suppressed antitumor immunity. The image is a transmission electron micrograph of a lymphocyte with the mitochondria stained purple. [Image: Don W. Fawcett/Science Source]