Research ArticleImmunology CARD9 mediates dendritic cell–induced development of Lyn deficiency–associated autoimmune and inflammatory diseases View ORCID ProfileJun Ma, View ORCID ProfileClare L. Abram, Yongmei Hu, and View ORCID ProfileClifford A. Lowell*Department of Laboratory Medicine and the Program in Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.↵*Corresponding author. Email: clifford.lowell{at}ucsf.edu See allHide authors and affiliations Science Signaling 08 Oct 2019:Vol. 12, Issue 602, eaao3829DOI: 10.1126/scisignal.aao3829 Jun Ma Department of Laboratory Medicine and the Program in Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Jun Ma Clare L. Abram Department of Laboratory Medicine and the Program in Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Clare L. Abram Yongmei Hu Department of Laboratory Medicine and the Program in Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Clifford A. Lowell Department of Laboratory Medicine and the Program in Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Clifford A. Lowell For correspondence: clifford.lowell@ucsf.edu Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 12 no. 602 DOI: https://doi.org/10.1126/scisignal.aao3829 PubMed: 31594855 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: Received July 14, 2017Accepted August 28, 2019 . Copyright & Usage: Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works http://www.sciencemag.org/about/science-licenses-journal-article-reuseThis is an article distributed under the terms of the Science Journals Default License. Author Information Altmetric Article usage Article lifetimeLast 6 monthsThis monthArticle usage: October 2019 to January 2021 AbstractFullPdf Oct 20194117372192 Nov 20191687450 Dec 20191024316 Jan 202086238 Feb 202081226 Mar 2020952115 Apr 2020811613 May 2020672124 Jun 202082144 Jul 202032207 Aug 2020352714 Sep 2020432918 Oct 2020285117 Nov 202025811 Dec 202045847 Jan 202132111 View Full Text
CARD9 mediates dendritic cell–induced development of Lyn deficiency–associated autoimmune and inflammatory diseases By Jun Ma, Clare L. Abram, Yongmei Hu, Clifford A. Lowell Science Signaling08 Oct 2019 Without the kinase Lyn, the adaptor protein CARD9 amplifies cytokine production in autoimmune disease. Supplementary Materials
CARD9 mediates dendritic cell–induced development of Lyn deficiency–associated autoimmune and inflammatory diseases By Jun Ma, Clare L. Abram, Yongmei Hu, Clifford A. Lowell Science Signaling08 Oct 2019 Without the kinase Lyn, the adaptor protein CARD9 amplifies cytokine production in autoimmune disease. Supplementary Materials