Contents
Vol 12, Issue 604
Research Articles
- An engineered pathway for N-hydroxy-pipecolic acid synthesis enhances systemic acquired resistance in tomato
Engineering a metabolite biosynthesis pathway in crop plants enhances systemic acquired resistance to pathogens.
- CD45 functions as a signaling gatekeeper in T cells
CD45 promotes strong but suppresses weak antigen-induced T cell receptor activation.
- Induction of metabolic quiescence defines the transitional to follicular B cell switch
Extracellular adenosine salvage and AMPK activation are enhanced in a stage-specific manner during human B cell development.
Editors' Choice
- A smoky path to diabetes
A nicotine-activated brain-pancreas circuit could explain why smokers are more likely to develop type 2 diabetes.
About The Cover

Online Cover This week features a Research Article that reports the engineering of tomato plants to produce a metabolite that enhances resistance to pathogens. The image shows a tomato plant. [Image: Andreea Ilin/shutterstock.com]