Contents

Research Articles

• An engineered pathway for N-hydroxy-pipecolic acid synthesis enhances systemic acquired resistance in tomato

  By Eric C. Holmes, Yun-Chu Chen, Elizabeth S. Sattely, Mary Beth Mudgett

  Science Signaling22 Oct 2019 Full AccessRestricted Access

  Engineering a metabolite biosynthesis pathway in crop plants enhances systemic acquired resistance to pathogens.

  • Editor's Summary
  • Abstract
  • Full Text
  • PDF
  • Supplementary Materials

• CD45 functions as a signaling gatekeeper in T cells

  By Adam H. Courtney, Alexey A. Shvets, Wen Lu, Gloria Griffante, Marianne Mollenauer, Veronika Horkova, Wan-Lin Lo, Steven Yu, Ondrej Stepanek, Arup K. Chakraborty, Arthur Weiss

  Science Signaling22 Oct 2019 Full AccessRestricted Access

  CD45 promotes strong but suppresses weak antigen-induced T cell receptor activation.

  • Editor's Summary
  • Abstract
  • Full Text
  • PDF
  • Supplementary Materials

• Induction of metabolic quiescence defines the transitional to follicular B cell switch

  By Jocelyn R. Farmer, Hugues Allard-Chamard, Na Sun, Maimuna Ahmad, Alice Bertocchi, Vinay S. Mahajan, Toby Aicher, Johan Arnold, Mark D. Benson, Jordan Morningstar, Sara Barmettler, Grace Yuen, Samuel J. H. Murphy, Jolan E. Walter, Musie Ghebremichael, Alex K. Shalek, Facundo Batista, Robert Gerszten, Shiv Pillai

  Science Signaling22 Oct 2019 Full AccessRestricted Access

  Extracellular adenosine salvage and AMPK activation are enhanced in a stage-specific manner during human B cell development.

  • Editor's Summary
  • Abstract
  • Full Text
  • PDF
  • Supplementary Materials