Contents
05 November 2019
Vol 12, Issue 606
Vol 12, Issue 606
Research Articles
- Nucleotide exchange–dependent and nucleotide exchange–independent functions of plant heterotrimeric GTP-binding proteins
G protein α subunits in Arabidopsis can function independently of guanine nucleotide exchange.
- TFEB drives PGC-1α expression in adipocytes to protect against diet-induced metabolic dysfunction
TFEB promotes the browning of white adipose tissue through mechanisms unrelated to autophagy.
- Extension of the Notch intracellular domain ankyrin repeat stack by NRARP promotes feedback inhibition of Notch signaling
NRARP interacts directly with the Notch transcriptional activation complex to inhibit signaling.
Editors' Choice
- Lactylation drives resolution
Histone modifications derived from the metabolite lactate promote transcription of genes necessary for the resolution of inflammation.
Erratum
- Erratum for the Research Article: “ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors” by A. Mamińska, A. Bartosik, M. Banach-Orłowska, I. Pilecka, K. Jastrzębski, D. Zdżalik-Bielecka, I. Castanon, M. Poulain, C. Neyen, L. Wolińska-Nizioł, A. Toruń, E. Szymańska, A. Kowalczyk, K. Piwocka, A. Simonsen, H. Stenmark, M. Fürthauer, M. González-Gaitán, M. Miaczynska
Fig. 4 and the legend for Fig. 5 have been updated.
About The Cover
Online Cover This week features a Research Article that shows that G protein α subunits in Arabidopsis can function independently of guanine nucleotide exchange. The image shows fluorescence-based detection of the plasma membrane localization of different G protein subunits in Nicotiana benthamiana leaves. [Image: Maruta et al./Science Signaling]
