Contents
26 November 2019
Vol 12, Issue 609
Vol 12, Issue 609
Research Articles
- Thiol-based direct threat sensing by the stress-activated protein kinase Hog1
Arsenic directly stimulates the kinase Hog1 to promote the gene expression required for arsenic detoxification in yeast.
- PKR-dependent cytosolic cGAS foci are necessary for intracellular DNA sensing
Intracellular DNA provokes cytoplasmic cGAS condensation, which requires the helicase G3BP1 and the RNA-dependent kinase PKR.
Research Resource
- The human secretome
A database provides information on the relative abundances and locations of human proteins that are predicted to be secreted.
Editors' Choice
- Trauma promotes resilience
Wounding induces cytoprotective mechanisms that make cells more resistant to oxidative damage.
About The Cover
Online Cover This week features a Research Article that reports that arsenic directly stimulates the kinase Hog1 to promote arsenic detoxification in yeast. The image shows a scanning electron micrograph of the yeast Saccharomyces cerevisiae with growing buds and bud scars. [Image: Eye of Science/Science Source]
