The human secretome

Mathias Uhlén; Max J. Karlsson; Andreas Hober; Anne-Sophie Svensson; Julia Scheffel; David Kotol; Wen Zhong; Abdellah Tebani; Linnéa Strandberg; Fredrik Edfors; Evelina Sjöstedt; Jan Mulder; Adil Mardinoglu; Anna Berling; Siri Ekblad; Melanie Dannemeyer; Sara Kanje; Johan Rockberg; Magnus Lundqvist; Magdalena Malm; Anna-Luisa Volk; Peter Nilsson; Anna Månberg; Tea Dodig-Crnkovic; Elisa Pin; Martin Zwahlen; Per Oksvold; Kalle von Feilitzen; Ragna S. Häussler; Mun-Gwan Hong; Cecilia Lindskog; Fredrik Ponten; Borbala Katona; Jimmy Vuu; Emil Lindström; Jens Nielsen; Jonathan Robinson; Burcu Ayoglu; Diana Mahdessian; Devin Sullivan; Peter Thul; Frida Danielsson; Charlotte Stadler; Emma Lundberg; Göran Bergström; Anders Gummesson; Bjørn G. Voldborg; Hanna Tegel; Sophia Hober; Björn Forsström; Jochen M. Schwenk; Linn Fagerberg; Åsa Sivertsson

doi:10.1126/scisignal.aaz0274

Research ResourceBiochemistry

The human secretome

Mathias Uhlén¹,²,³,*,
Max J. Karlsson¹,
Andreas Hober¹,
Anne-Sophie Svensson⁴,
Julia Scheffel⁴,
David Kotol¹,
Wen Zhong¹,
Abdellah Tebani¹,
Linnéa Strandberg¹,
Fredrik Edfors¹,⁵,
Evelina Sjöstedt³,
Jan Mulder³,
Adil Mardinoglu¹,
Anna Berling⁴,
Siri Ekblad⁴,
Melanie Dannemeyer⁴,
Sara Kanje⁴,
Johan Rockberg⁴,
Magnus Lundqvist⁴,
Magdalena Malm⁴,
Anna-Luisa Volk⁴,
Peter Nilsson¹,
Anna Månberg¹,
Tea Dodig-Crnkovic¹,
Elisa Pin¹,
Martin Zwahlen¹,
Per Oksvold¹,
Kalle von Feilitzen¹,
Ragna S. Häussler¹,
Mun-Gwan Hong¹,
Cecilia Lindskog⁶,
Fredrik Ponten⁶,
Borbala Katona⁶,
Jimmy Vuu⁶,
Emil Lindström⁶,
Jens Nielsen⁷,
Jonathan Robinson⁷,
Burcu Ayoglu¹,
Diana Mahdessian¹,
Devin Sullivan¹,
Peter Thul¹,
Frida Danielsson¹,
Charlotte Stadler¹,
Emma Lundberg¹,
Göran Bergström⁸,⁹,
Anders Gummesson⁸,
Bjørn G. Voldborg²,
Hanna Tegel⁴,
Sophia Hober⁴,
Björn Forsström¹,
Jochen M. Schwenk¹,
Linn Fagerberg¹, and
Åsa Sivertsson¹

¹Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.
²Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
³Department of Neuroscience, Karolinska Institute, Stockholm, Sweden.
⁴Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.
⁵Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA.
⁶Department of Pathology, Uppsala University, Uppsala, Sweden.
⁷Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
⁸Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
⁹Region Västra Götaland, Sahlgrenska University Hospital, Department of Clinical Physiology, Gothenburg, Sweden.

↵*Corresponding author. Email: mathias.uhlen{at}scilifelab.se

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Science Signaling 26 Nov 2019:
Vol. 12, Issue 609, eaaz0274
DOI: 10.1126/scisignal.aaz0274

Mathias Uhlén

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.Department of Neuroscience, Karolinska Institute, Stockholm, Sweden.

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For correspondence: mathias.uhlen@scilifelab.se

Max J. Karlsson

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Andreas Hober

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Anne-Sophie Svensson

Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Julia Scheffel

Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.

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David Kotol

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Wen Zhong

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Abdellah Tebani

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Linnéa Strandberg

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Fredrik Edfors

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA.

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Evelina Sjöstedt

Department of Neuroscience, Karolinska Institute, Stockholm, Sweden.

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Jan Mulder

Department of Neuroscience, Karolinska Institute, Stockholm, Sweden.

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Adil Mardinoglu

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Anna Berling

Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Siri Ekblad

Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Melanie Dannemeyer

Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Sara Kanje

Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Johan Rockberg

Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Magnus Lundqvist

Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Magdalena Malm

Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Anna-Luisa Volk

Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Peter Nilsson

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Anna Månberg

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Tea Dodig-Crnkovic

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Elisa Pin

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Martin Zwahlen

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Per Oksvold

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Kalle von Feilitzen

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Ragna S. Häussler

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Mun-Gwan Hong

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Cecilia Lindskog

Department of Pathology, Uppsala University, Uppsala, Sweden.

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Fredrik Ponten

Department of Pathology, Uppsala University, Uppsala, Sweden.

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Borbala Katona

Department of Pathology, Uppsala University, Uppsala, Sweden.

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Jimmy Vuu

Department of Pathology, Uppsala University, Uppsala, Sweden.

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Emil Lindström

Department of Pathology, Uppsala University, Uppsala, Sweden.

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Jens Nielsen

Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.

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Jonathan Robinson

Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.

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Burcu Ayoglu

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Diana Mahdessian

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Devin Sullivan

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Peter Thul

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Frida Danielsson

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Charlotte Stadler

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Emma Lundberg

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Göran Bergström

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.Region Västra Götaland, Sahlgrenska University Hospital, Department of Clinical Physiology, Gothenburg, Sweden.

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Anders Gummesson

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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Bjørn G. Voldborg

Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.

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Hanna Tegel

Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Sophia Hober

Department of Protein Science, AlbaNova University Center, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Björn Forsström

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Jochen M. Schwenk

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Linn Fagerberg

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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Åsa Sivertsson

Department of Protein Science, Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

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vol. 12 no. 609

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https://doi.org/10.1126/scisignal.aaz0274

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Received August 6, 2019
Accepted November 12, 2019
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Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works http://www.sciencemag.org/about/science-licenses-journal-article-reuseThis is an article distributed under the terms of the Science Journals Default License.

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The human secretome

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