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Research ResourcePhysiology
Metabolic rewiring of the hypertensive kidney
- View ORCID ProfileMarkus M. Rinschen1,2,
- View ORCID ProfileOleg Palygin3,
- View ORCID ProfileCarlos Guijas1,
- View ORCID ProfileAmelia Palermo1,
- View ORCID ProfileNicolas Palacio-Escat4,5,6,
- View ORCID ProfileXavier Domingo-Almenara1,
- View ORCID ProfileRafael Montenegro-Burke1,
- View ORCID ProfileJulio Saez-Rodriguez4,5,7,
- View ORCID ProfileAlexander Staruschenko3,8,*, and
- View ORCID ProfileGary Siuzdak1,*
- 1Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute, La Jolla, CA 92122, USA.
- 2Department II of Internal Medicine and Center for Molecular Medicine, University of Cologne, Cologne 50931, Germany.
- 3Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
- 4COMBINE-Joint Research Center for Computational Biomedicine RWTH Aachen University, Aachen 52074, Germany.
- 5Institute of Computational Biomedicine, Bioquant, Faculty of Medicine and Heidelberg University Hospital, Heidelberg University, Heidelberg 69120, Germany.
- 6Faculty of Biosciences, University of Heidelberg, Heidelberg 69120, Germany.
- 7Molecular Medicine Partnership Unit (MMPU), European Molecular Biology Laboratory and Heidelberg University, Heidelberg 69120, Germany.
- 8Clement J. Zablocki VA Medical Center, Milwaukee, WI 53295, USA.
- ↵*Corresponding author. Email: staruschenko{at}mcw.edu (A.S.); siuzdak{at}scripps.edu (G.S.)
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Science Signaling 10 Dec 2019:
Vol. 12, Issue 611, eaax9760
DOI: 10.1126/scisignal.aax9760
Vol. 12, Issue 611, eaax9760
DOI: 10.1126/scisignal.aax9760
Markus M. Rinschen
1Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute, La Jolla, CA 92122, USA.
2Department II of Internal Medicine and Center for Molecular Medicine, University of Cologne, Cologne 50931, Germany.
Oleg Palygin
3Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Carlos Guijas
1Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute, La Jolla, CA 92122, USA.
Amelia Palermo
1Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute, La Jolla, CA 92122, USA.
Nicolas Palacio-Escat
4COMBINE-Joint Research Center for Computational Biomedicine RWTH Aachen University, Aachen 52074, Germany.
5Institute of Computational Biomedicine, Bioquant, Faculty of Medicine and Heidelberg University Hospital, Heidelberg University, Heidelberg 69120, Germany.
6Faculty of Biosciences, University of Heidelberg, Heidelberg 69120, Germany.
Xavier Domingo-Almenara
1Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute, La Jolla, CA 92122, USA.
Rafael Montenegro-Burke
1Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute, La Jolla, CA 92122, USA.
Julio Saez-Rodriguez
4COMBINE-Joint Research Center for Computational Biomedicine RWTH Aachen University, Aachen 52074, Germany.
5Institute of Computational Biomedicine, Bioquant, Faculty of Medicine and Heidelberg University Hospital, Heidelberg University, Heidelberg 69120, Germany.
7Molecular Medicine Partnership Unit (MMPU), European Molecular Biology Laboratory and Heidelberg University, Heidelberg 69120, Germany.
Alexander Staruschenko
3Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
8Clement J. Zablocki VA Medical Center, Milwaukee, WI 53295, USA.
Gary Siuzdak
1Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute, La Jolla, CA 92122, USA.
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