07 January 2020
Vol 13, Issue 613

About The Cover

Cover image expansion

Online Cover This week features a Research Article that shows that disease-associated mutations in strumpellin, a component of the WASH complex, which plays a role in endosomal sorting, impair cell adhesion and spreading by disrupting integrin recycling. The image shows actin (red) and nuclei (blue) in a human retinal pigment epithelial cell line in which strumpellin was knocked down by RNA interference. [Image: Lee et al./Science Signaling]