Research ArticleGPCR SIGNALING
The GPCR accessory protein MRAP2 regulates both biased signaling and constitutive activity of the ghrelin receptor GHSR1a
- View ORCID ProfileAlix A. J. Rouault1,
- Luciana K. Rosselli-Murai2,
- View ORCID ProfileCiria C. Hernandez3,
- View ORCID ProfileLuis E. Gimenez3,
- View ORCID ProfileGregory G. Tall2, and
- View ORCID ProfileJulien A. Sebag1,*
- 1Department of Molecular Physiology and Biophysics, Fraternal Order of Eagles Diabetes Research Center, Iowa Neuroscience Institute, Pappajohn Biomedical Institute, University of Iowa, Iowa City, IA 52242, USA.
- 2Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA.
- 3Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
- ↵*Corresponding author. Email: julien-sebag{at}uiowa.edu
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Science Signaling 07 Jan 2020:
Vol. 13, Issue 613, eaax4569
DOI: 10.1126/scisignal.aax4569
Vol. 13, Issue 613, eaax4569
DOI: 10.1126/scisignal.aax4569
Alix A. J. Rouault
1Department of Molecular Physiology and Biophysics, Fraternal Order of Eagles Diabetes Research Center, Iowa Neuroscience Institute, Pappajohn Biomedical Institute, University of Iowa, Iowa City, IA 52242, USA.
Luciana K. Rosselli-Murai
2Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA.
Ciria C. Hernandez
3Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
Luis E. Gimenez
3Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
Gregory G. Tall
2Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA.
Julien A. Sebag
1Department of Molecular Physiology and Biophysics, Fraternal Order of Eagles Diabetes Research Center, Iowa Neuroscience Institute, Pappajohn Biomedical Institute, University of Iowa, Iowa City, IA 52242, USA.
