Contents
Vol 13, Issue 614
Research Articles
- The Vibrio cholerae MARTX toxin silences the inflammatory response to cytoskeletal damage before inducing actin cytoskeleton collapse
The multifunctional MARTX toxin of Vibrio cholerae damages host cells and suppresses the innate response to that damage.
- Single-molecule imaging reveals the oligomeric state of functional TNFα-induced plasma membrane TNFR1 clusters in cells
Ligand binding triggers the oligomerization of TNFR1 monomers and dimers into trimers and higher-order oligomers.
Editors' Choice
- Predicting resistance to KRAS inhibitors
Studies identify common targets for preventing resistance to KRAS inhibitors.
About The Cover

Online Cover This week features a Research Article that shows how a multifunctional Vibrio cholerae toxin simultaneously damages cells and suppresses inflammation. The image is a colorized light micrograph of V. cholerae. [Image: James Cavallini/Science Source]