05 May 2020
Vol 13, Issue 630

About The Cover

Cover image expansion

Online Cover This week features a Research Article that shows how spinal delivery of Hsp90 inhibitors can enhance the efficacy of systemically administered opioids. The image shows synthetic opioid peptide–induced ERK phosphorylation (green) in lumbar spine tissue slices from mice treated intrathecally with vehicle (top) or an Hsp90 inhibitor (bottom). [Image: Duron et al./Science Signaling]