Contents
21 July 2020
Vol 13, Issue 641
Vol 13, Issue 641
Research Articles
- Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration
The progression of inflammation-associated colon cancer is driven by resident bacteria.
- Redox priming promotes Aurora A activation during mitosis
CoAlation of the kinase Aurora A induces an open dimer conformation that facilitates its activation.
- Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation
Structural and functional analyses suggest that the hub domain of CaMKII regulates kinase activity.
Editors' Choice
- New connections: Redox regulation of kinases
Several studies glean insight into how kinases are structurally regulated by reversible oxidation.
About The Cover
Online Cover This week features a Research Article that shows how an oral commensal bacterium associated with periodontal disease promotes the metastatic progression of colon cancer. The image shows a colored scanning electron micrograph of Fusobacterium nucleatum. [Image: Dennis Kunkel Microscopy/Science Source]
