18 August 2020
Vol 13, Issue 645

About The Cover

Cover image expansion

Online Cover This week features a Research Article that finds that the DNA demethylase TET2 mediates sensitivity to PARP inhibitors by promoting the degradative processing of stalled replication forks. The image shows a chromosome spread from U2OS cells overexpressing TET2 and treated with hydroxyurea. [Image: S. Burkett/National Cancer Institute, USA]