29 September 2020
Vol 13, Issue 651

About The Cover

Cover image expansion

Online Cover This week features a Research Article that reports several crystal structures of a SARS-CoV-2 methyltransferase that is critical for mRNA capping in complex with various combinations of its methyl donor and cap structure substrates, a reaction product, and an inhibitor. The image shows the two subunits of the methyltransferase in complex with the methyl donor SAM (green) and two Zn2+ ions (purple). [Image: Rosas-Lemus et al./Science Signaling]