Contents

Research Articles

• Airway relaxation mechanisms and structural basis of osthole for improving lung function in asthma

  By Sheng Wang, Yan Xie, Yan-Wu Huo, Yan Li, Peter W. Abel, Haihong Jiang, Xiaohan Zou, Hai-Zhan Jiao, Xiaolin Kuang, Dennis W. Wolff, You-Guo Huang, Thomas B. Casale, Reynold A. Panettieri Jr., Taotao Wei, Zhengyu Cao, Yaping Tu

  Science Signaling24 Nov 2020 Full AccessRestricted Access

  A compound derived from a traditional Chinese medicine targets a phosphodiesterase to induce airway relaxation.

  • Editor's Summary
  • Abstract
  • Full Text
  • PDF

• Kallikrein 13 serves as a priming protease during infection by the human coronavirus HKU1

  By Aleksandra Milewska, Katherine Falkowski, Magdalena Kulczycka, Ewa Bielecka, Antonina Naskalska, Pawel Mak, Adam Lesner, Marek Ochman, Maciej Urlik, Elftherios Diamandis, Ioannis Prassas, Jan Potempa, Tomasz Kantyka, Krzysztof Pyrc

  Science Signaling24 Nov 2020 Full AccessRestricted Access

  The protease kallikrein 13 cleaves the spike protein of the human coronavirus HKU1 to facilitate viral entry.

  • Editor's Summary
  • Abstract
  • Full Text
  • PDF
  • Supplementary Materials