Contents
Vol 14, Issue 670
Research Articles
- Ligand-independent activity of the ghrelin receptor modulates AMPA receptor trafficking and supports memory formation
Blocking the constitutive activity of the ghrelin receptor impairs spatial and recognition memory.
- A predictive model of gene expression reveals the role of network motifs in the mating response of yeast
Signaling network motifs ensure appropriate transcriptional responses to distinct pheromone dynamics in yeast.
Editors' Choice
- Drugging mutant p53
Arsenic trioxide may be effective against tumors with structural p53 mutations.
Erratum
- Erratum for the Research Article: “Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists” by A. Gillis, A. B. Gondin, A. Kliewer, J. Sanchez, H. D. Lim, C. Alamein, P. Manandhar, M. Santiago, S. Fritzwanker, F. Schmiedel, T. A. Katte, T. Reekie, N. L. Grimsey, M. Kassiou, B. Kellam, C. Krasel, M. L. Halls, M. Connor, J. R. Lane, S. Schulz, M. J. Christie, M. Canals
Incorrect data entries in tables in the paper and Supplementary Materials have been corrected.
About The Cover

Online Cover This week features a Research Article that shows that blocking the constitutive activity of the ghrelin receptor impairs spatial and recognition memory in mice. The image shows fluorescent staining of cultured murine hippocampal neurons. [Image: Ribeiro et al./Science Signaling]