Research ArticleSystems Biology A predictive model of gene expression reveals the role of network motifs in the mating response of yeast View ORCID ProfileAmy E. Pomeroy1,†, View ORCID ProfileMatthew I. Peña2,*,†, John R. Houser2, Gauri Dixit3, View ORCID ProfileHenrik G. Dohlman3, View ORCID ProfileTimothy C. Elston2,4,‡, and View ORCID ProfileBeverly Errede3,‡1Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.2Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.3Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.4Computational Medicine Program, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.↵‡Corresponding author. Email: errede{at}email.unc.edu (B.E.); telston{at}med.unc.edu (T.C.E.)↵* Present address: Department of BioSciences, Rice University, Houston, TX 77005, USA.↵† These authors contributed equally to this work. See allHide authors and affiliations Science Signaling 16 Feb 2021:Vol. 14, Issue 670, eabb5235DOI: 10.1126/scisignal.abb5235 Amy E. Pomeroy 1Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Amy E. Pomeroy Matthew I. Peña 2Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Matthew I. Peña John R. Houser 2Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Gauri Dixit 3Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Henrik G. Dohlman 3Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Henrik G. Dohlman Timothy C. Elston 2Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.4Computational Medicine Program, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Timothy C. Elston For correspondence: errede@email.unc.edu telston@med.unc.edu Beverly Errede 3Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Beverly Errede For correspondence: errede@email.unc.edu telston@med.unc.edu Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 14 no. 670 DOI: https://doi.org/10.1126/scisignal.abb5235 PubMed: 33593998 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: Received March 3, 2020Accepted January 8, 2021 . Copyright & Usage: Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works https://www.sciencemag.org/about/science-licenses-journal-article-reuseThis is an article distributed under the terms of the Science Journals Default License. Author Information Altmetric Article usage Article lifetimeLast 6 monthsThis monthArticle usage: February 2021 to March 2021 AbstractFullPdf Feb 20214515415148 Mar 2021671411 View Full Text
A predictive model of gene expression reveals the role of network motifs in the mating response of yeast By Amy E. Pomeroy, Matthew I. Peña, John R. Houser, Gauri Dixit, Henrik G. Dohlman, Timothy C. Elston, Beverly Errede Science Signaling16 Feb 2021 Signaling network motifs ensure appropriate transcriptional responses to distinct pheromone dynamics in yeast. Supplementary Materials
A predictive model of gene expression reveals the role of network motifs in the mating response of yeast By Amy E. Pomeroy, Matthew I. Peña, John R. Houser, Gauri Dixit, Henrik G. Dohlman, Timothy C. Elston, Beverly Errede Science Signaling16 Feb 2021 Signaling network motifs ensure appropriate transcriptional responses to distinct pheromone dynamics in yeast. Supplementary Materials