Contents

Research Articles

• A peptide of the N terminus of GRK5 attenuates pressure-overload hypertrophy and heart failure

  By Ryan C. Coleman, Akito Eguchi, Melissa Lieu, Rajika Roy, Eric W. Barr, Jessica Ibetti, Anna-Maria Lucchese, Amanda M. Peluzzo, Kenneth Gresham, J. Kurt Chuprun, Walter J. Koch

  Science Signaling30 Mar 2021 Full AccessRestricted Access

  GRK5 does not mediate pathological signaling in the heart if its nuclear translocation is disrupted.

  • Editor's Summary
  • Abstract
  • Full Text
  • PDF
  • Supplementary Materials

• Inositol 1,4,5-trisphosphate 3-kinase B promotes Ca²⁺ mobilization and the inflammatory activity of dendritic cells

  By Laura Marongiu, Francesca Mingozzi, Clara Cigni, Roberta Marzi, Marco Di Gioia, Massimiliano Garrè, Dario Parazzoli, Laura Sironi, Maddalena Collini, Reiko Sakaguchi, Takashi Morii, Mariacristina Crosti, Monica Moro, Stéphane Schurmans, Tiziano Catelani, Rany Rotem, Miriam Colombo, Stephen Shears, Davide Prosperi, Ivan Zanoni, Francesca Granucci

  Science Signaling30 Mar 2021 Full AccessRestricted Access

  Inflammatory responses of dendritic cells in vitro and in vivo require IP₄ generated by the kinase ITPKB.

  • Editor's Summary
  • Abstract
  • Full Text
  • PDF
  • Supplementary Materials