FocusImmunology

The spatial distribution of target cell ligands determines NK cell degranulation

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Science Signaling  25 May 2021:
Vol. 14, Issue 684, eabi8525
DOI: 10.1126/scisignal.abi8525

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Abstract

Cell-bound ligands are often viewed as moving passively in response to displacement of their cognate receptors. Verron et al. provide an example of the distribution of ligands influencing the functional outcome of receptor stimulation.

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