15 June 2021
Vol 14, Issue 687

About The Cover

Cover image expansion

Online Cover This week features a Research Article that shows that the transmembrane receptor Tim-3, which is often considered to be an inhibitory factor, is recruited to the immune synapse between an antigen-presenting cell (APC) and a T cell, where it provides stimulatory signals that enable T cell activation. The image is a three-dimensional illustration of an APC activating multiple T cells. [Image: Juan Gaertner/Science Source]