Research ArticleCancer Biology
Only a Subset of Met-Activated Pathways Are Required to Sustain Oncogene Addiction
- Andrea Bertotti1,
- Mike F. Burbridge2,*,
- Stefania Gastaldi1,*,
- Francesco Galimi1,*,
- Davide Torti1,*,
- Enzo Medico3,
- Silvia Giordano1,
- Simona Corso1,
- Gaëlle Rolland-Valognes4,
- Brian P. Lockhart4,
- John A. Hickman2,
- Paolo M. Comoglio1,†, and
- Livio Trusolino1,†
- 1Division of Molecular Oncology, Institute for Cancer Research and Treatment (IRCC), University of Torino Medical School, 10060 Candiolo (Torino), Italy.
- 2Cancer Research and Drug Discovery, Institut de Recherches Servier, 78290 Croissy-sur-Seine, France.
- 3Laboratory of Functional Genomics, The Oncogenomics Center, Institute for Cancer Research and Treatment (IRCC), University of Torino Medical School, 10060 Candiolo (Torino), Italy.
- 4Division of Molecular Pharmacology and Pathophysiology, Institut de Recherches Servier, 78290 Croissy-sur-Seine, France.
- ↵†To whom correspondence should be addressed. E-mail: livio.trusolino{at}ircc.it (L.T.) and paolo.comoglio{at}ircc.it (P.M.C.)
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Science Signaling 08 Dec 2009:
Vol. 2, Issue 100, pp. ra80
DOI: 10.1126/scisignal.2000643
