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vol. 2 no. 102 ra85
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History:
- Received April 21, 2009
- Accepted December 4, 2009
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Copyright © 2009, American Association for the Advancement of Science
Research ArticleCell Biology
Tumor Suppression by PTEN Requires the Activation of the PKR-eIF2α Phosphorylation Pathway
- Zineb Mounir1,2,
- Jothi Latha Krishnamoorthy1,
- Gavin P. Robertson3,
- Donalyn Scheuner4,
- Randal J. Kaufman4,
- Maria-Magdalena Georgescu5, and
- Antonis E. Koromilas1,6,*
- 1Lady Davis Institute for Medical Research, Sir Mortimer B. Davis–Jewish General Hospital, Montreal, Quebec, Canada H3T 1E2.
- 2Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada H3A 1A3.
- 3Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
- 4Biological Chemistry and Internal Medicine and the Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor, MI 48109, USA.
- 5Department of Molecular Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
- 6Department of Oncology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada H2W 1S6.
- ↵*To whom correspondence should be addressed. E-mail: antonis.koromilas{at}mcgill.ca
See allHide authors and affiliations
Science Signaling 22 Dec 2009:
Vol. 2, Issue 102, pp. ra85
DOI: 10.1126/scisignal.2000389
Vol. 2, Issue 102, pp. ra85
DOI: 10.1126/scisignal.2000389
Zineb Mounir
Lady Davis Institute for Medical Research, Sir Mortimer B. Davis–Jewish General Hospital, Montreal, Quebec, Canada H3T 1E2.Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada H3A 1A3.
Jothi Latha Krishnamoorthy
Lady Davis Institute for Medical Research, Sir Mortimer B. Davis–Jewish General Hospital, Montreal, Quebec, Canada H3T 1E2.
Gavin P. Robertson
Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
Donalyn Scheuner
Biological Chemistry and Internal Medicine and the Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor, MI 48109, USA.
Randal J. Kaufman
Biological Chemistry and Internal Medicine and the Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor, MI 48109, USA.
Maria-Magdalena Georgescu
Department of Molecular Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Antonis E. Koromilas
Lady Davis Institute for Medical Research, Sir Mortimer B. Davis–Jewish General Hospital, Montreal, Quebec, Canada H3T 1E2.Department of Oncology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada H2W 1S6.
