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Abstract
This is a conversation about research highlighted in the Editors’ Choice summary titled “The Long Way Around.” The highlighted article is E. Hinoi, N. Gao, D. Y. Jung, V. Yadav, T. Yoshizawa, M. G. Myers Jr., S. C. Chua Jr., J. K. Kim, K. H. Kaestner, G. Karsenty, The sympathetic tone mediates leptin’s inhibition of insulin secretion by modulating osteocalcin bioactivity. J. Cell Biol. 183, 1235–1242 (2008).