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vol. 2 no. 63 ra12
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History:
- Received December 18, 2008
- Accepted March 6, 2009
- .
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Copyright © 2009, American Association for the Advancement of Science
Research ArticleBiochemistry
An Intramolecular Switch Regulates Phosphoindependent FHA Domain Interactions in Mycobacterium tuberculosis
- Timothy J. Nott1,
- Geoff Kelly2,
- Lasse Stach1,
- Jiejin Li1,
- Sarah Westcott1,
- Dony Patel1,
- Debbie M. Hunt3,
- Steven Howell1,
- Roger S. Buxton3,
- Helen M. O’Hare4,5, and
- Stephen J. Smerdon1,*
- 1Division of Molecular Structure, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
- 2Biomedical NMR Centre, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
- 3Division of Mycobacterial Research, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
- 4Department of Infection, Immunity and Inflammation, University of Leicester, Leicester LE1 9HN, UK.
- 5Department of Biochemistry, University of Leicester, Leicester LE1 9HN, UK.
- ↵*To whom correspondence should be addressed. E-mail: stephen.smerdon{at}nimr.mrc.ac.uk
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Science Signaling 24 Mar 2009:
Vol. 2, Issue 63, pp. ra12
DOI: 10.1126/scisignal.2000212
Vol. 2, Issue 63, pp. ra12
DOI: 10.1126/scisignal.2000212
Timothy J. Nott
1Division of Molecular Structure, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
Geoff Kelly
2Biomedical NMR Centre, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
Lasse Stach
1Division of Molecular Structure, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
Jiejin Li
1Division of Molecular Structure, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
Sarah Westcott
1Division of Molecular Structure, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
Dony Patel
1Division of Molecular Structure, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
Debbie M. Hunt
3Division of Mycobacterial Research, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
Steven Howell
1Division of Molecular Structure, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
Roger S. Buxton
3Division of Mycobacterial Research, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
Helen M. O’Hare
4Department of Infection, Immunity and Inflammation, University of Leicester, Leicester LE1 9HN, UK.
5Department of Biochemistry, University of Leicester, Leicester LE1 9HN, UK.
Stephen J. Smerdon
1Division of Molecular Structure, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
