PresentationCOMPUTATIONAL BIOLOGY

Molecular Origin and Functional Consequences of Digital Signaling and Hysteresis During Ras Activation in Lymphocytes

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Science Signaling  14 Apr 2009:
Vol. 2, Issue 66, pp. pt2
DOI: 10.1126/scisignal.266pt2

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vol. 2 no. 66 pt2

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Author Information

  1. Arup K. Chakraborty1,2,3,,
  2. Jayajit Das1,*,
  3. Julie Zikherman4,
  4. Ming Yang1,
  5. Christopher C. Govern1,
  6. Mary Ho5,,
  7. Arthur Weiss4,6, and
  8. Jeroen Roose5
  1. 1Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
  2. 2Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
  3. 3Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
  4. 4Division of Rheumatology, Department of Medicine, University of California, 513 Parnassus Avenue, San Francisco, CA 94143, USA.
  5. 5Department of Anatomy, University of California, 513 Parnassus Avenue, San Francisco, CA 94143, USA.
  6. 6Howard Hughes Medical Institute, University of California, 513 Parnassus Avenue, San Francisco, CA 94143, USA.
  7. *Present address: Battelle Center for Mathematical Medicine, Nationwide Children's Hospital and Department of Pediatrics, and Biophysics Graduate Program, Ohio State University, 700 Children's Drive, Columbus, OH 43205, USA.
  8. Present address: Graduate School of Physical Therapy, Samuel Merritt University, 450 30th Street, Suite 2800, Oakland, CA 94609, USA.
  1. Presenter and corresponding author. E-mail, arupc{at}mit.edu

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