Research ArticleG Proteins
Gαi1 and Gαi3 Are Required for Epidermal Growth Factor–Mediated Activation of the Akt-mTORC1 Pathway
- Cong Cao1,2,
- Xuesong Huang1,
- Yuyuan Han1,
- Yinsheng Wan3,
- Lutz Birnbaumer4,
- Geng-Sheng Feng5,
- John Marshall6,
- Meisheng Jiang7, and
- Wen-Ming Chu1,2,*
- 1Department of Molecular Microbiology and Immunology, Brown University, Providence, RI 02912, USA.
- 2Pathobiology Graduate Program, Brown University, Providence, RI 02912, USA.
- 3Department of Biology, Providence College, Providence, RI 02918, USA.
- 4Laboratory of Neurobiology, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.
- 5Burnham Institute for Medical Research, La Jolla, CA 92037, USA.
- 6Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, RI 02912, USA.
- 7Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
- ↵*To whom correspondence should be addressed. E-mail: wen-ming_chu{at}brown.edu
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Science Signaling 28 Apr 2009:
Vol. 2, Issue 68, pp. ra17
DOI: 10.1126/scisignal.2000118
