Research ArticleIon Channels TRPM1 Forms Ion Channels Associated with Melanin Content in Melanocytes Elena Oancea1,*,†, Joris Vriens1,‡, Sebastian Brauchi1,§, Janice Jun1, Igor Splawski2, and David E. Clapham11Howard Hughes Medical Institute, Department of Cardiology, Children’s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.2Novartis Institutes for BioMedical Research, Inc., Cambridge, MA 02139, USA.↵†To whom correspondence should be addressed. E-mail: Elena_Oancea{at}Brown.edu ↵* Present address: Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, RI 02912, USA. ↵‡ Present address: Laboratory for Ion Channel Research, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium. ↵§ Present address: Laboratory of Sensory Physiology, Department of Physiology, Universidad Austral de Chile, Valdivia, 511-0566, Chile. See allHide authors and affiliations Science Signaling 12 May 2009:Vol. 2, Issue 70, pp. ra21DOI: 10.1126/scisignal.2000146 Elena Oancea 1Howard Hughes Medical Institute, Department of Cardiology, Children’s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site For correspondence: Elena_Oancea@Brown.edu Joris Vriens 1Howard Hughes Medical Institute, Department of Cardiology, Children’s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Sebastian Brauchi 1Howard Hughes Medical Institute, Department of Cardiology, Children’s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Janice Jun 1Howard Hughes Medical Institute, Department of Cardiology, Children’s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Igor Splawski 2Novartis Institutes for BioMedical Research, Inc., Cambridge, MA 02139, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site David E. Clapham 1Howard Hughes Medical Institute, Department of Cardiology, Children’s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 2 no. 70 ra21 DOI: https://doi.org/10.1126/scisignal.2000146 PubMed: 19436059 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: Received November 19, 2008Accepted April 24, 2009 . Copyright & Usage: Copyright © 2009, American Association for the Advancement of Science Author Information Altmetric Article usage Article lifetimeLast 6 monthsThis monthArticle usage: May 2009 to March 2021 AbstractFullPdf May 20091409243269 Jun 20091259766 Jul 20091146238 Aug 2009634939 Sep 2009574929 Oct 2009836035 Nov 2009886260 Dec 2009613937 Jan 20101043427 Feb 2010604227 Mar 2010712921 Apr 2010613024 May 2010762331 Jun 2010533538 Jul 2010513728 Aug 20101361310 Sep 2010811819 Oct 2010841824 Nov 201075617 Dec 2010541312 Jan 2011671621 Feb 2011701420 Mar 201171615 Apr 2011531513 May 201150511 Jun 201148712 Jul 20115668 Aug 20115378 Sep 20114837 Oct 201137713 Nov 201152211 Dec 2011501013 Jan 2012651812 Feb 2012501210 Mar 201254912 Apr 2012692313 May 2012702113 Jun 20123523 Jul 201242311 Aug 20125178 Sep 2012331213 Oct 201244812 Nov 2012351511 Dec 2012481411 Jan 2013541212 Feb 201343179 Mar 201340127 Apr 201341149 May 201337109 Jun 201349105 Jul 20135896 Aug 2013452310 Sep 201323108 Oct 201358915 Nov 201355109 Dec 2013631012 Jan 20144356 Feb 201440149 Mar 2014432014 Apr 201434148 May 2014562510 Jun 201450156 Jul 20145673 Aug 201417102 Sep 201423104 Oct 20143494 Nov 20141824 Dec 20143139 Jan 20152597 Feb 20151056 Mar 201522136 Apr 2015544 May 20152132 Jun 20153012 Jul 20151824 Aug 20151312 Sep 201519412 Oct 2015634 Nov 2015637 Dec 20153713 Jan 20164345 Feb 20162811 Mar 20164828 Apr 20162623 May 20164042 Jun 20165731 Jul 20165767 Aug 20165244 Sep 20165117 Oct 20166715 Nov 20167252 Dec 20165832 Jan 20172712 Feb 20175123 Mar 20173903 Apr 20174635 May 20173627 Jun 20171713 Jul 20174343 Aug 20174713 Sep 20172911 Oct 20173214 Nov 20175732 Dec 20177521 Jan 201812242 Feb 201812546 Mar 201861913 Apr 20183492 May 20185534 Jun 20185747 Jul 20185055 Aug 201825136 Sep 20183232 Oct 201848127 Nov 2018392616 Dec 201835184 Jan 20192863 Feb 201952102 Mar 20194953 Apr 201917115 May 201935144 Jun 20192961 Jul 20192764 Aug 20191996 Sep 20191572 Oct 201942287 Nov 20193863 Dec 20193653 Jan 202023157 Feb 20201395 Mar 20204499 Apr 20202152 May 20201592 Jun 202013132 Jul 202021149 Aug 202013121 Sep 20202098 Oct 202026136 Nov 202020109 Dec 202021124 Jan 202124153 Feb 20211550 Mar 2021900 View Full Text
TRPM1 Forms Ion Channels Associated with Melanin Content in Melanocytes By Elena Oancea, Joris Vriens, Sebastian Brauchi, Janice Jun, Igor Splawski, David E. Clapham Science Signaling12 May 2009 : ra21 Newly identified TRPM1 isoforms that mediate current are highly conserved, present intracellularly, and associated with melanin content.
TRPM1 Forms Ion Channels Associated with Melanin Content in Melanocytes By Elena Oancea, Joris Vriens, Sebastian Brauchi, Janice Jun, Igor Splawski, David E. Clapham Science Signaling12 May 2009 : ra21 Newly identified TRPM1 isoforms that mediate current are highly conserved, present intracellularly, and associated with melanin content.