Editorial GuideSystems Biology

“Omic” Risk Assessment

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Science Signaling  26 May 2009:
Vol. 2, Issue 72, pp. eg7
DOI: 10.1126/scisignal.272eg7

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Integration of data from different techniques is the key to effective validation of “hits” in large-scale screens. A discussion of validation methods for siRNA screens and protein-interaction screens reveals how to go beyond an arbitrary assignment of relevant to a more biologically meaningful identification of targets.

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